A Case of Inconspicuous Recurrent Herpes Labialis Mimicking Unilateral Angular Cheilitis

Masita Mandasari, Ambar Kusuma Astuti, Febrina Rahmayanti


Recurrent herpes labialis (RHL) is a common manifestation of herpes simplex virus (HSV) reactivation inimmunocompetent individuals, whereas angular cheilitis is an inflammatory lesion occurring on one or bothlip commissures and is induced by local and/or systemic conditions. We describe a case of RHL er uption on thecorner of the mouth, easily mistaken as angular cheilitis. Case Report: A 21-year-old male presented to our dental hospital with a 3 day history of a painful, unilateral lesion on the left corner of his mouth. The lesion featured anerythematous base with a yellowish crust that extended outward. We diagnosed the lesion as RHL. We prescribedchlorhexidine solution and topical acyclovir to be applied onto the lesion. At 2 weeks follow-up, the lesion wasresolved. An RHL lesion that er upts on the corner of the mouth may initially resemble angular cheilitis. However,the typical clinical presentation, history of recurrence, and the absence of predisposing factors for other lesionssuggested an infection caused by HSV. Conclusion: RHL which occurred at one side of the mouth corner canbe similar with unilateral AC. But, detailed history taking and clinical observation led to correct diagnosis andmanagement.


Angular Cheilitis; Diagnosis; Herpes Simplex Virus; Recurrent herpes labialis

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